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Conn's syndrome is also very rare, caused by a benign adenoma or hyperplasia of the zona glomerulosa producing excess aldosterone.
The zona granulosa cells begin to secrete progesterone (granulosa lutein cells ).
The egg is surrounded by a special coat called the zona pellucida.
For fertilization to occur, a sperm must penetrate the tough outer membrane of the egg called the zona pellucida.
When one sperm successfully binds with the zona pellucida, a series of chemical reactions occurs to allow only that sperm to penetrate.