What-s-up meaning

(idiomatic, colloquial) What are you doing?; what is happening?
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(informal) How are you?; how are you feeling?
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(idiomatic, colloquial) What’s the matter?
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(rhetorical question, colloquial) A casual greeting with a meaning similar to how are you? or nice to meet you.
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Origin of what-s-up

  • Made popular by the cartoon character Bugs Bunny who used it as early as 1940 as part of his catch phrase “What’s up Doc?”.
    From Wiktionary