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Progeny vaccinia and human cytomegalovirus particles utilize early endosomal cisternae for their envelopes.
One experimental approach has used a virus called vaccinia into which the gene for PSA had been cloned.
Regulation of plaque size and host range by a vaccinia virus gene related to complement system proteins.
The project will start by looking at the vaccinia type I topoisomerase enzyme.
Vaccinia infection of cells can confer protection from IFN on other viruses, e.g. Picornaviruses.