SSRIs should not be used with any drug that increases serotonin concentrations, including MAO inhibitors, tramadol, sibutramine, meperidine, sumatriptan, lithium, St. John's wort, ginkgo biloba, and some anti-psychotic agents.
Sibutramine - Marketed as Meridia, sibutramine works to suppress appetite and is used in conjunction with diet and exercise to help individuals lose weight.
Sibutramine, Meridia's active ingredient and Orlistat found in Xenical are both chemically-based compounds.
Meridia is manufactured by Abbott Pharmaceutical Company and is the brand name for sibutramine.
There are several known side effects that have occurred with the use of sibutramine.