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This form of EDS is caused by a change in the enzyme called procollagen I N-terminal peptidase.
Catalytic Type The catalytic type of a peptidase relates to the chemical groups responsible for its catalysis of peptide bond hydrolysis.
This gives an indication of whether a novel sequence is that of an active peptidase or a non-peptidase homologue.
This shows whether we currently regard this as an ' active ', ' putative ' or ' inactive ' peptidase homologue.
This sequence is subsequently cleaved off (by signal peptidase ).
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