In the spring of 334, Alexander crossed with an army of between 30,000 and 40,000 men, Macedonians, Illyrians, Thracians and the contingents of the Greek states, into Asia.
Macedonians, and at Prophthasia the commander of the Macedonian cavalry Philotas, the son of Parmenio, and certain others were arraigned before the army on the charge of conspiring against the king's life.
These opposed a national resistance to the Macedonians, the fires of which were fanned by the Brahmins, but still the strong arm of the western people prevailed.
This policy did not allay the discontent of the Macedonian army, and when Alexander in the summer of 324 moved to the cooler region of Media, an actual mutiny of the Macedonians broke out on the way at Opis on the Tigris.
Alexander had planned to amalgamate the former rulers of the world with his Macedonians; but his death was followed by a Macedonian reaction.