Light-chain definition

The smaller of the two types of polypeptide chains in immunoglobulins, consisting of an antigen-binding portion with a variable amino acid sequence, and a constant region with an amino acid sequence that is relatively unchanging.

Either of the two smaller polypeptide chains in an immunoglobulin molecule, consisting of an antigen-binding portion with a variable amino acid sequence and a constant region that occurs in two different forms in humans.

The smaller of the two types of polypeptide chains in an antibody molecule. A light chain consists of an antigen-binding portion with a variable amino acid sequence, and a constant region with an amino acid sequence that is relatively unchanging. The light chains are attached to the heavy chains so that the variable regions of both lie alongside each other.