A few years ago, I was in this romantic comedy (A Family Affair) and I played the ex-girlfriend of the lead character.
It was that role which led to her true breakout performance, as the lead character in Speed with Keanu Reeves.
Lowe played Sam Seaborn, who was at first, the lead character in the story.
Award-winning actress and producer Jane Seymour is best known for her role as the lead character in the 1990s television series Dr. Quinn, Medicine Woman.
Another lead character in the series is Sam Axe played by Bruce Campbell.