Fifth Disease Definition

A mild viral disease occurring mainly in early childhood, characterized by fever, a rosy-red rash on the cheeks that often spreads to the trunk and limbs, and usually arthritis and malaise.
American Heritage

(pathology) The manifestation as rashes of an infection by erythrovirus.


Origin of Fifth Disease

  • Historically classified as the fifth of the classical childhood skin rashes or exanthems, after measles, scarlet fever, rubella, and Dukes' disease.

    From Wiktionary

  • From its being fifth in frequency of rash-producing childhood diseases

    From American Heritage Dictionary of the English Language, 5th Edition

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fifth disease