Comet assay results were given for 8 organs in the mouse with 208 chemicals for which carcinogenicity bioassay data were available.
Long term animal carcinogenicity bioassays are currently in progress.
The Committee agreed that the negative rat inhalation carcinogenicity bioassay provided additional reassurance with regard to possible site of contact mutagenicity.
rat carcinogenicity study for humans are not yet clarified.
The mechanism and relevance of these findings in the rat carcinogenicity study for humans are not yet clarified.