If taken with other metabolites that aid in the creation of serotonin - vitamin B, niacin and magnesium, which a multivitamin should provide - 5HTP can help deal with many of the same health issues that people take tryptophan for.
Alternative treatment of high cholesterol may include high doses of garlic, niacin, soy protein, algae, or other fatty acids, and the Chinese medicine supplement Cholestin (a red yeast fermented with rice).
Though niacin side effects are mostly positive and have been shown to have many health benefits, taking more than the recommended daily allowance should only be done under the direction of a doctor.
Pauling was already interested in vitamin therapy after his own successful treatment of Bright's disease and other books he'd read previously about the use of niacin as a therapeutic agent.
Cantaloupe contains other vitamins and minerals including 5% of the USRDA for thiamin, 2% of the USRDA for riboflavin, 6% of the USRDA for vitamin B6 and 6% of the USRDA for niacin.