(4) Isoquinoline group. The opium alkaloids: morphine, codeine, thebaine, papaverine, narcotine, narceine, &c.; and the complicated substances hydrastine and berberine.
A second paper, published in 1817, was followed in the same year by the identification of a new base, narcotine, by P. J.
The alkaloids fall into two chemical groups: (i) derivatives of isoquinoline, including papaverine, narcotine, gnoscopine (racemic narcotine), narceine, laudanosine, laudanine, cotarnine, hydrocotarnine (the last two do not occur in opium), and (2) derivatives of phenanthrene, including morphine, codeine, thebaine.
Narcotine, C22H23N07, has been principally investigated by A.
Narcotine was shown to be methoxyhydrastine (II.) (hydrastine, the alkaloid of Golden seal, Hydrastis canadensis, was solved by E.