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micronucleus Definition

micro·nu·cleus (mī′krō no̵̅o̅klē əs, -nyo̵̅o̅-)

noun

the smaller of two types of nuclei present in the cells of ciliated protozoans, associated primarily with reproduction and genetics

Related Forms:

micronucleus Usage Examples

Preposition: in

  • marrow: Howe, J. ( 2002 ) 1,3-Dichloropropan-2-ol ( 1,3-DCP ): Induction of micronuclei in the bone marrow of treated rats.
  • lymphocyte: Increases chromosome aberrations and micronuclei in human blood lymphocytes.
  • erythrocyte: In relation to the analysis for micronuclei in peripheral erythrocytes, it was noted that the spleen could have removed damaged cells.
  • cell: Neither did anakinra increase the incidence of chromosomal abnormalities or micronuclei in bone marrow cells in mice.

Adjective modifier

  • positive: Overall, it was felt that the data on centromere positive micronuclei should be considered in more detail.

Modifies a noun

  • assay: A negative result had been reported in an adequate oral bone marrow mouse micronucleus assay.
  • test: At the latter time point negative results were obtained in a micronucleus test using peripheral blood.
  • formation: These new data indicate that phenol can produce hypothermia in mice at doses that result in micronuclei formation.
  • frequency: Of the 10 related women without the familial mutation, only 2 had clearly enhanced micronucleus frequencies.

Noun used with modifier

  • bone-marrow: The Committee considered the new in vivo rat bone-marrow micronucleus test.
  • in-vivo: In the first instance this should be in the in-vivo bone marrow micronucleus assay.
  • in-vitro: It was noted that the in-vitro micronucleus task group had come to somewhat disappointing conclusions regarding agreement on methodology.
  • marrow: A negative result had been reported in an adequate oral bone marrow mouse micronucleus assay.
  • vitro: Indicate that the Committee believes that routine screening for aneugenicity is possible using the in vitro micronucleus assay with centromeric staining.
  • rat: The Committee considered the new in vivo rat bone-marrow micronucleus test.