first lady

  1. the wife or official hostess of a chief official, esp. of the U.S. president, a state governor, or a mayor
  2. a woman considered to be foremost in her profession or art

See first lady in American Heritage Dictionary 4

noun
  1. often First Lady The wife or hostess of the chief executive of a country, state, or city.
  2. The foremost woman of a specified profession, group, or art: the first lady of the American theater.

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