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An effective immune response is likely to induce changes in local tumor vasculature as immune effectors are recruited.
The example here shows 3-D images of vasculature in vivo, obtained using two-photon fluorescence excitation.
Images concentrate on the bony landmarks and the major thoracic and abdominal viscera, the musculature and peripheral vasculature.
Fibrinogen E fragment selectively disrupts the vasculature and inhibits the growth of murine tumors in a syngeneic murine model.
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