Production of cells by the spleen will increase to meet the demands of accelerated RBC destruction (hemolysis).
We have also studied S. pupula demes using molecular sequence data, from 18S rDNA, ITS and rbc L sequences.
Since white cells may enter the CSF in response to local infection, inflammation, or bleeding, the RBC count is used to correct the WBC count so that it reflects conditions other than hemorrhage or a traumatic tap.
It is characterized by low hemoglobin and unusually small and fragile RBCs (microcytosis), although the RBC count may be normal.
A reticulocyte (young RBCs) count will help determine if anemia is caused by impaired RBC production or increased RBC destruction.