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There is diverse opinion and a lack of consensus about management of preterm birth due to the lack of clinical and scientific data.
This changed dramatically with the administration of supplemental oxygen to preterm infants in the late 1940s.
Very low birthweight infants with clinical seizures have a higher incidence of impairment than preterm infants without seizures 34.
Pregnant women infected with syphilis are also at increased risk for miscarriage, preterm labor, and stillbirth.
However there is no proof that routine intubation of all very preterm babies leads to decreased morbidity.
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