Sentence Examples

  • The porphyrias are disorders in which the body produces too much porphyrin and insufficient heme (an iron-containing nonprotein portion of the hemoglobin molecule).
  • Owing to deficient ferrochelatase, the last step in the heme biosynthesis pathway-the insertion of an iron atom into a porphyrin molecule-cannot be completed.
  • The presence and estimated quantity of porphyrin and protoporphyrins in biological samples are easily detected using spectrofluorometric testing.
  • If the porphyria becomes symptomatic, the common factor between all types is an abnormal accumulation of protoporphyrins or porphyrin.
  • In the past, the porphyrias were divided into two general categories based on the location of the porphyrin production.