Alessandro de Medici was placed there with the title of duke of Civit di Penna; and, on his murder in 1537, Cosimo de Medici, of the younger branch of the ruling house, was made duke.
In 1715 Fathers Desideri and Freyre made their way from Agra, across the Himalayas, to Lhasa, and the Capuchin Friar Orazio della Penna resided in that city from 1735 until 1747.
In 1906 Dr Affonso Penna, three times minister under Pedro II., and at that time governor of the state of Minas-Geraes, of which he had founded the new capital, Bello Horizonte, was elected president, a choice due to a coalition of the other states against Sao Paulo, to which all the recent presidents had belonged.
Penna's presidency was distinguished by his successful efforts to place the finances on a sound basis.
This scholarly linguist, equipped with modern methods of scientific research, did not confine himself to the classical period like Csoma, but extended his ' The Capuchin friars who were settled in Lhasa for a quarter of a century from 1719 studied the language; two of them, Francisco Orazio della Penna, well known from his accurate description of Tibet, and Cassian di Macerata sent home materials which were utilized by the Augustine friar Aug.