P53 Definition

A protein that regulates normal cell growth and proliferation and prevents unrestrained cell division after chromosomal damage, as from ultraviolet or ionizing radiation. The absence of functional p53, usually resulting from a genetic mutation, increases the risk of developing various cancers.
American Heritage
The tumor suppressor gene that codes for this protein.
American Heritage Medicine

Origin of P53

  • p(rotein) 53 from its apparent molecular mass of 53 kilodaltons as extrapolated from its mobility during electrophoresis

    From American Heritage Dictionary of the English Language, 5th Edition