Factors contributing to this poor outlook include the presence of locally advanced disease and undiagnosed metastases at presentation.
bony metastases is usually localized, except where there is associated nerve involvement or damage.
Professor Taylor's main clinical and research interests lie in surgical oncology but particularly colorectal cancer and colorectal liver metastases.
colorectal cancer metastases have single or multiple metastases with no extra hepatic disease.
Other symptoms of distant metastases are sciatica, lymph node enlargement, swelling in the lower limbs.