The long bones of the limbs consist of an axis of cartilage; the extremities of the cartilages frequently undergo calcification and are thus converted into epiphyses.
The bones here were very friable whilst other long bones appeared reasonably strong.
The bones are involved 50 to 75 percent of the time, which includes the skull, or mandible, and the long bones.
In this condition, the epiphyseal plates of the long bones of the body do not close, and they remain responsive to additional stimulated growth by hGH.
Achondroplasia-A congenital disturbance of growth plate development in long bones that results in a person having shortened limbs and a normal trunk.