Last-straw definitions

The last of a series of annoyances or disappointments that leads one to a final loss of patience, temper, trust, or hope.
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The last of a sequence of annoyances or troubles that results in a breakdown, loss of patience, etc.
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(slang) A small addition to a burden which causes it to exceed the capacity.

That's the last straw; it's a petty demand but I'm already under too much work. I quit!

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Origin of last-straw

From the proverb “It's the last straw that breaks the camel's back”