Anyone who has a primary immunodeficiency is going to face problems.
Combined immunodeficiency has been reported in long-haired dachshunds and in basset hounds.
The course of infection tends to be more serious in children who are immunocompromised, such as those undergoing chemotherapy or those who have a disease that disrupts normal immune response (e.g. human immunodeficiency syndrome [HIV]).
Whether we believe that HIV or fear is the major co-factor in acquired immunodeficiency, it is a deadly combination.
This may be particularly important for female relatives on the maternal side of a family where a male baby has an X-linked immunodeficiency.