Cushing-s-syndrome definition

ko͝oshĭngz
A syndrome caused by an increased production of ACTH from a tumor of the adrenal cortex or of the anterior lobe of the pituitary gland, or by excessive intake of glucocorticoids. It is characterized by obesity and weakening of the muscles.
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A medical condition characterized by obesity, hypertension, excessive hair growth, etc., caused by an overactive adrenal gland or large doses of corticosteroids.
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A syndrome caused by an excess of corticosteroids, especially cortisol, in the blood, characterized by obesity, muscle and skin atrophy, facial fullness (known as moon facies ), hypertension, and other physical changes. Glucocorticoid excess is usually caused by a tumor of the adrenal cortex, excessive intake of ACTH or glucocorticoids, or increased production of ACTH from a tumor of the anterior lobe of the pituitary gland. Cushing's syndrome is named after its discoverer, American neurosurgeon Harvey Williams Cushing (1869–1939).
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(medicine) Hyperadrenocorticism or hypercorticism, an endocrine disorder caused by high levels of cortisol in the blood.
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Origin of cushing-s-syndrome

  • After Harvey Williams Cushing

    From American Heritage Dictionary of the English Language, 5th Edition