Some of these children developed carditis and valvular disease.
The most serious problem occurring in RF is called pancarditis ("pan" means total; "carditis" refers to inflammation of the heart).
Mild carditis also improves with such anti-inflammatory agents, although more severe cases of carditis require steroid medications.
The long-term prognosis of an RF patient depends primarily on whether he or she develops carditis.
Those patients with no or mild carditis have an excellent prognosis.