Pestis, pestilentia), in medicine, a term given to any epidemic disease causing a great mortality, and used in this sense by Galen and the a ncient medical writers, but now confined to a special disease, otherwise called Oriental, Levantine, or Bubonic Plague, which may be shortly defined a specific infectious fever, one variety being characterized by buboes (glandular swellings) and carbuncles.
It appeared in Gaul in 546, where it is described by Gregory of Tours with the same symptoms as lues inguinaria (from the frequent seat of buboes in the groin).
In the second of these, which occurred in the Ahmedabad district of the Bombay Presidency in 1683-89, buboes ale distinctly described.
The Bombay Plague Research Committee, whose experience is unequalled, say: " In a number of instances points of inoculation were found on the extremities of patients, from which plague cultures were obtained, and in these cases buboes were found above the point of inoculation.
The really pathognomonic sign is the appearance of buboes or inflamed glands, which happens early in the illness, usually on the second day; sometimes they are present from the outset, sometimes they cannot be detected before the third day, or even later.