Sometimes the buboes are multiple and on both sides, but more commonly they are unilateral.
(2) Rufus speaks of the buboes called pestilential as being specially fatal, and as being found chiefly in Libya, Egypt and Syria, He refers to the testimony of a physician Dionysius, who lived probably in the 3rd century B.C. or earlier, as and to Dioscorides and Posidonius, who fully described these buboes in a work on the plague which prevailed in Libya in their time.
pestis, pestilentia), in medicine, a term given to any epidemic disease causing a great mortality, and used in this sense by Galen and the a ncient medical writers, but now confined to a special disease, otherwise called Oriental, Levantine, or Bubonic Plague, which may be shortly defined a specific infectious fever, one variety being characterized by buboes (glandular swellings) and carbuncles.
It appeared in Gaul in 546, where it is described by Gregory of Tours with the same symptoms as lues inguinaria (from the frequent seat of buboes in the groin).
In the second of these, which occurred in the Ahmedabad district of the Bombay Presidency in 1683-89, buboes ale distinctly described.