Amphiphilic Definition

ămfə-fĭlĭk
adjective
Of or relating to a molecule having a polar, water-soluble group attached to a nonpolar, water-insoluble hydrocarbon chain.
American Heritage

(chemistry, of a molecule) Being a detergent: having both hydrophilic and hydrophobic (lipophilic) groups.

Wiktionary
(biochemistry, of a protein, especially an alpha helix) Having one surface consisting of hydrophilic amino acids and the opposite surface consisting of hydrophobic (lipophilic) ones.
Wiktionary
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