Allosteric Definition

Of or involving a change in the shape and activity of an enzyme that results from molecular binding with a regulatory substance at a site other than the enzymatically active one.
American Heritage
Of or having to do with a protein with a structure that is altered reversibly by a small molecule so that its original function is modified.
Webster's New World
Of or relating to the binding of a molecule to an enzyme at a site other than the active site, resulting in modulation of the enzyme's activity as a result of a change in its shape.
American Heritage Medicine

(biochemistry, of an enzyme) That binds a compound on an inactive site and thus changes conformation in order to become either active or inactive.


Origin of Allosteric

  • allo- (“other”) +‎ steric (“arrangement of atoms in space”)

    From Wiktionary

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