The fortress was rebuilt, and after 280 served the Aetolians as a bulwark against Celts and Macedonians.
- Aegina passed with the rest of Greece under the successive dominations of Macedon, the Aetolians, Attalus of Pergamum and Rome.
In 192 Antiochus invaded Greece, having the Aetolians and other Greek states as his allies.
During the struggle of the Aetolians against Rome it stood a stubborn siege.
The legend of an organized apportionment of Peloponnese amongst the Heracleid leaders appears first in the 5th-century tragedians, - not earlier, that is, than the rise of the Peloponnesian League, - and was amplified in the 4th century; the Aetolians' aid, and claim to Elis, appear first in Ephorus.