Sentence Examples

  • Hantzsch (Ann., 1882, 215, p. I; Ber., 1882, 15, p. 2914) which consists in the condensation of two molecules of aceto-acetic ester with one of an aldehyde and one of ammonia: RO 2 C CH 2 R' CHO CH 2 CO 2 R RO 2 C C CHR' C C02R CH 3 CO + NH 3 + CO CH 3 -' CH3 C-NH-C CH3 The resulting dihydro-compound is then oxidized with nitrous acid, the ester hydrolysed and the resulting acid heated with lime; carbon dioxide is eliminated and a trisubstituted pyridine of the type CH C(CH3) is obtained.

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