substantia nigrasubstantia ni·gra
pl. sub·stan′tiae· ni′grae , sub·stan′tia ni′gras
a layer of dark cells in the midbrain that produce dopamine
Origin of substantia nigraModL, black substance
A layer of large pigmented nerve cells in the midbrain that produce dopamine and whose destruction is associated with Parkinson's disease.
Origin of substantia nigraNew Latin : Latin substantia, substance + Latin nigra, feminine of niger, black.
(plural substantiae nigrae or substantia nigras)
- A brain structure located in the mesencephalon (midbrain) that plays an important role in reward, addiction, and movement, damage to which occurs in Parkinson's and Parkinsonian patients.
Directly from Latin meaning the black body or substance.