penetrance

Preposition: of

• mutation: However, the penetrance of the major haemochromatosis mutations is not accurately known.
• gene: The penetrance of the disease gene is ~ 75 % .
• genotype: The etiology of both conditions could be further complicated by variable penetrance of the various genotypes and the involvement of environmental factors.
• haemochromatosis: News Stories Very low penetrance of hereditary haemochromatosis Low mortality from untreated haemochromatosis?

Converse of object

• have: Whether the cat is heterozygous or homozygous for W, the blue eyes and deafness have incomplete penetrance.
• show: AB - PURPOSE: To identify the mutation in the RB1 gene in a Syrian family showing incomplete penetrance of retinoblastoma ( RB ).
• decrease: However, decreased penetrance of a particular gene defect cannot be excluded.

Adjective modifier

• incomplete: Incomplete penetrance refers to absence of disease despite presence of the dominant disease gene.
• reduced: There is a 50 per cent chance of parents passing on the gene, although with reduced penetrance.
• variable: A better understanding of the factors that underlie variable penetrance in mutation carriers is needed to augment our ability to counsel individual women.
• low: Last November, the HFEA launched a public debate on testing embryos for ' lower penetrance ' , late onset genetic disorders.
• high: All these conditions are ' high penetrance ' - meaning that people who have the gene are extremely likely to develop the condition.
• Very: News Stories Very low penetrance of hereditary haemochromatosis Low mortality from untreated haemochromatosis?

Modifies a noun

• gene: Where there are known rare, high penetrance susceptibility genes ( e.g.
• susceptibility: Where there are known rare, high penetrance susceptibility genes ( e.g.
• estimate: Therefore, penetrance estimates will tend to be inflated.