monoclonal

Converse of object

• commercialize: CAT has alliances with a large number of pharmaceutical and biotechnology companies to discover, develop and commercialize human monoclonal antibody-based products.
• develop: AB - A patient with multiple myeloma was treated with several cycles of chemotherapy and developed monoclonal IgA rheumatoid factor.
• use: Of interest is the Dynabeads assay, an alternative method for providing CD4 cell counts using anti-CD4 monoclonal antibody-coated magnetic beads.

Adjective modifier

• human: Clinical Outcome of Colorectal Cancer Patients treated with Human monoclonal anti-idiotypic antibody.

Modifies a noun

• antibody: Look in our clinical trials database for monoclonal antibody trials - type ' antibody ' in the free text search box.
• gammopathy: These observations induced us to suspect a monoclonal gammopathy.
• therapeutics: CAT will receive royalty payments on sales of any human monoclonal antibody therapeutics that Enzon and Micromet successfully develop using CAT's intellectual property.
• anti-d: If clear positive results are not obtained with two monoclonal anti-D reagents it is safer to classify the patient as D negative.
• reagent: This recommendation applies also to human donations used in the preparation of monoclonal antibody reagents.
• therapy: New strategies such as monoclonal antibody therapy and molecular targeted small molecule therapy are becoming a reality in the treatment of many diseases.

Noun used with modifier

• rat: The original rat monoclonal antibodies had been prepared from ascitic fluid, crudely fractionated with ammonium sulfate.
• mouse: Negative controls utilized a mouse monoclonal antibody raised against a non-mammalian epitope.
• anti-tnf: HUMIRA TM HUMIRA ( adalimumab ) is a human anti-TNF monoclonal antibody which was isolated and optimized by CAT in collaboration with Abbott Laboratories.
• rodent: A solution to the immunogenicity of rodent monoclonal antibodies in human therapy would be to derive human antibodies directly from humans.
• alpha: Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab.
• anti-ige: Long-term asthma control with omalizumab, an anti-IgE monoclonal antibody in patients with severe allergic asthma.