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macrophage Definition

macro·phage (makrō fāj′)

noun

any of various large, phagocytic cells in connective tissue, lymphatic tissue, bone marrow, etc. of vertebrates

Etymology: macro- + -phage

macrophage Related Forms

mac′ro·phagic (-fajik) adjective

macrophage Usage Examples

Converse of object

  • activate: These activated macrophages then migrate to draining lymph nodes, where they stimulate naive T cells ( Ref.
  • call: Creates large killer cells called macrophages or ' big eaters ' along with other types of immune system fighter cells.
  • include: Other types of white blood cells include macrophages and neutrophils.
  • target: David is well known for his expertise in using gene targeted macrophages to deliver cytokines to inflamed sites to provide in vivo biosensors.
  • infect: Changes in gene transcription in macrophages infected with M. tuberculosis are being monitored using an Affymetrix gene chip array system.

Converse of subject

produce: IL-6 is another of the inflammatory cytokines produced by macrophages.

Adjective modifier

  • alveolar: The researchers will study the pattern of release of interleukins by alveolar macrophages that have been treated with fibers.
  • human: Background The laboratory has previously identified a pathway by which infected human macrophages are induced to kill intracellular mycobacteria rapidly.
  • infected: Background The laboratory has previously identified a pathway by which infected human macrophages are induced to kill intracellular mycobacteria rapidly.
  • tumour-associated: The role of tumour-associated macrophages in tumor progression: implications for new anti-cancer therapies.

Modifies a noun

  • infiltration: Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma.
  • activation: Efficacy of cyclosporine A in the treatment of macrophage activation syndrome in juvenile arthritis: Report of five cases.
  • colony: The cells were collected after the daughter was given granulocyte macrophage colony stimulating factor for 5 days to boost her white blood cells.
  • migration: Title of Research What controls macrophage migration inhibitory factor in inflammatory arthritis?
  • cell: Once in certain tissues they probably cause inflammation by stimulating macrophage cells.
  • function: This herb stimulates the immune system in several different ways, including enhancing macrophage function and increasing T-cell response.

Noun used with modifier

  • granulocyte: The cells were collected after the daughter was given granulocyte macrophage colony stimulating factor for 5 days to boost her white blood cells.
  • tissue: They can leave the blood stream and are then referred to as tissue macrophages.
  • mouse: Novel triterpenoids suppress inducible nitric oxide synthase and inducible cyclooxygenase in mouse macrophages.

Preposition: in

vitro: Antagonistic effects of different classes of bisphosphonates in osteoclasts and macrophages in vitro.