Van't Hoff and Le Bel, occupies such a position in organic chemistry that its value can never be transcended.
Wislicenus, Le Bel and van 't Hoff has resulted in the introduction of another condition which formulae for the benzene complex must satisfy, viz.
This subject has occupied a dominant position in physico-chemical research since the investigations of van't Hoff and Arrhenius.
This is shown in the case of the chloracetic acids: According to van 't Hoff the substitution of chlorine atoms into a methyl group occasions the following increments: The introduction of chlorine, however, may involve a fall in the boiling-point, as is recorded by Henry in the case of the chlorinated acetonitriles: NC CH 3.
Van't Hoff, Lectures on Theoretical and Physical Chemistry; J.