A Y-shaped protein on the surface of B cells that is secreted into the blood or lymph in response to an antigenic stimulus, such as a bacterium, virus, parasite, or transplanted organ, and that neutralizes the antigen by binding specifically to it; an immunoglobulin.
Origin: Translation of German Antikrper : anti-, antagonistic (from Latin anti-, anti-) + Krper, body.
When bacteria enter a flesh wound, a B lymphocyte releases antibodies, which collect the bacteria and direct them toward a macrophage for destruction.
Abbr. Ab A protein substance produced in the blood or tissues in response to a specific antigen, such as a bacterium or a toxin, that destroys or weakens bacteria and neutralizes organic poisons, thus forming the basis of immunity.
An immunoglobulin present in the blood serum or body fluids as a result of antigenic stimulus and interacting only with the antigen that induced it or with an antigen closely related to it.
Any of numerous proteins produced by B lymphocytes in response to the presence of specific foreign antigens, including microorganisms and toxins. Antibodies consist of two pairs of polypeptide chains, called heavy chains and light chains, that are arranged in a Y-shape. The two tips of the Y are the regions that bind to antigens and deactivate them. Also called immunoglobulin.
A Closer Look Like other vertebrates, humans possess an effective immune system that uses antibodies to fight bacteria, viruses, and cancer cells. Antibodies are complex, Y-shaped protein molecules. The immune system's B lymphocytes, which are produced by the bone marrow, develop into plasma cells that can generate a huge variety of antibodies, each one capable of combining with and destroying an antigen, a foreign molecule. Antibodies react to very specific characteristics of different antigens, binding them to the top ends of their Y formation. Once the antibody and antigen combine, the antibodies deactivate the antigen or lead it to macrophages(a kind of white blood cell) that ingest and destroy it. High numbers of a particular antibody may persist for months after an invasion, eventually diminishing. However, the B cells can quickly manufacture more of the same antibody if exposure to the antigen recurs. Vaccines work by “training” B cells to recognize and react quickly to potential disease molecules.