In the 6th century Alexander of Tralles used colchicum for gout, iron for anaemia, and rhubarb in liver weakness and dysentery.
In chronic cases the eventual effects are anaemia, melanosis, enlargement of the spleen and liver, and general cachexia.
ANKYLOSTOMIASIS, or Anchylostomiasis (also called helminthiasis, "miners' anaemia," and in Germany Wurmkrank- heit), a disease to which in recent years much attention has been paid, from its prevalence in the mining industry in England, France, Germany, Belgium, North Queensland and elsewhere.
The parasites, which cling to the intestinal mucous membrane, draw their nourishment from the blood-vessels of their host, and as they are found in hundreds in the body after death, the disorders of digestion, the increasing anaemia and the consequent dropsies and other cachectic symptoms are easily explained.
The origin of the corpuscles, previously a matter of so much difference of opinion, is now pretty fairly set at rest, and has proved the key to the interpretation of the pathology of many diseases of the blood, such as the different forms of anaemia, of leucocythaemia, &c.
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