Secondary amines yield nitrosamines, R 2 N NO, with nitrous acid.
With nitrous acid, the primary amines yield alcohols, the secondary amines yield nitrosamines and the tertiary amines do not react: Rï¿½NH 2 +0NOH= Rï¿½OH+N2+H20; R2NH+ [[Onoh= R 2 Nï¿½No H]] 2 0.
Both classes readily exchange the imide hydrogen for acid radicals, and give nitrosamines with nitrous acid.
Diazo-Amines.-The diazo-amines, R N: N NHR I, are obtained by the action of primary amines on diazonium salts; by the action of nitrous acid on a free primary amine, an isodiazohydroxide being formed as an intermediate product which then condenses with the amine; and by the action of nitrosamines on primary amines.
The nitrogen can also transform into nitrites, which can combine with the proteins in food to form nitrosamines, which are carcinogenic.