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transaminase Definition

trans·ami·nase (--amə nās′, -nāz′)

noun

any of a group of enzymes that cause transamination

Etymology: < transamination + -ase

transaminase Usage Examples

Modifies a noun

  • elevation: In Phase III RESIST trials, the frequency of transaminase elevations was significantly increased in the APTIVUS/ritonavir arm compared to the comparator arm.
  • activity: Laboratory findings included acid urine despite alkali therapy and elevated serum transaminase activities.
  • level: In the majority of cases, liver transaminase levels have returned to their baseline value without the need for treatment discontinuation.
  • increase: These transaminase increases were likely to be related to the skeletal muscle effects.

Noun used with modifier

  • alanine: Elevated bilirubin, alanine transaminase and lactate dehydrogenase concentrations are indicative of hepatocellular injury.
  • serum: Laboratory findings included acid urine despite alkali therapy and elevated serum transaminase activities.
  • plasma: It may account for up to 90 % of isolated increases of plasma transaminase of otherwise unknown cause.
  • liver: In the majority of cases, liver transaminase levels have returned to their baseline value without the need for treatment discontinuation.
  • oxaloacetate: Blocks the malate / aspartate cycle by inhibiting glutamate - oxaloacetate transaminase ( GOT ).