tamoxifen Definition
ta·moxi·fen (tə mäk′sə fen′)
noun
a synthetic hormone, CHNO, used as an estrogen-blocking drug to inhibit the growth of certain types of tumors, esp. in cases of advanced breast cancer: in full tamoxifen citrate
tamoxifen Usage Examples
Converse of object
- take: In most women the benefits of taking tamoxifen outweigh the risks.
- receive: The main finding was a 49 % reduction in the incidence of breast cancer among the participants who were randomly assigned to receive tamoxifen.
- use: The risk is small compared to the benefits of using tamoxifen to treat breast cancer.
- compare: Review This review sought information on all trials in early breast cancer begun before 1990 comparing adjuvant tamoxifen versus no such treatment.
- show: Tamoxifen A randomized controlled trial has shown that tamoxifen reduces the risk of developing breast cancer in women at increased risk for the disease.
- give: They were either given 20 mg tamoxifen daily for five years or a placebo.
Preposition: for
- cancer: Tamoxifen for early breast cancer: an overview of the randomized trials.
- prevention: There are other ongoing randomized trials in Europe testing the efficacy of tamoxifen for the primary prevention of breast cancer.
- woman: There have been a few studies of tamoxifen for women who have advanced ovarian cancer that hasn't responded to chemotherapy treatment.
Adjective modifier
adjuvant: Randomized trial of two versus five years of adjuvant tamoxifen for post-menopausal early stage breast cancer.
Modifies a noun
- therapy: These appear to persist despite four years of tamoxifen therapy and increase prior to relapse in some patients.
- treatment: The included trials were conducted in women with metastatic breast cancer after the failure of the tamoxifen treatment.
- citrate: Tamoxifen citrate is the only approved chemopreventive agent for breast cancer.
- trial: McDonald CC, Stewart HJ: Fatal myocardial infarction in the Scottish adjuvant tamoxifen trial.
Noun used with modifier
- drug: The thought came to mind after we looked at the success of the drug tamoxifen in fighting - and preventing - breast cancer.
- term: Q: Regarding the therapeutic effects of estrogens, more more women these days are on long term tamoxifen for breast cancer.
- treatment: Hormone treatment Doctors have been looking at the hormone treatment tamoxifen to treat advanced ovarian cancer.

