The amount of natural foods allowed in a diet can be adjusted to ensure that the level of phenylalanine in the blood is kept within a safe range-2 to 6 mg/dL before 12 years of age and 2 to 15 mg/dL for PKU patients over 12 years old.
If the initial PKU test produces a positive result, then follow-up tests are performed to confirm the diagnosis and to determine if the elevated phenylalanine levels may be caused by some medical condition other than PKU.
They have highlighted the urgent need for consistent international standards for proper management of PKU patients, which should emphasize comprehensive psychological as well as physiological monitoring and assessment.
Ideally, school-age children with PKU should be taught to assume responsibility for managing their diets, recording food intake, and for performing simple blood tests to monitor their phenylalanine levels.
Phenylalanine is of course dangerous to people with the inherited genetic condition called PKU, but it's also dangerous for people who have unrecognized mood disorders masquerading as depression.