Streptococci, meningococci, and Haemophilus influenzae, organisms that cause diseases such as otitis media, sinusitis, pneumonia, meningitis, osteomyelitis, septic arthritis, and sepsis, all make capsules.
In children, these systemic (affecting the whole body) or disseminated infections frequently affect the ends of the long bones of the arms or legs, causing a bone infection called osteomyelitis.
Left untreated, however, it may develop into a serious disease, including osteomyelitis (bone infection), septic arthritis (joint infection), or pneumonia.
The child has two or more deep-seated infections (meningitis, osteomyelitis, sepsis, or cellulitis).
Infections of the bones and joints leading to arthritis or osteomyelitis.