Macrinus was defeated at Nisibis and concluded a peace with Artabanus, in which he gave up all the Roman conquests, restored the booty, and paid a heavy contribution to the Parthians (Dio Cass.
Its main centres were at Edessa and Nisibis, but it was the literary language of practically all the Christian writers in the region east of Antioch, as well as of the Christian subjects of the Persian empire.
NISIBIS (Nasibina in the Assyrian inscriptions), an ancient city and fortress in the north of Mesopotamia, near the point where the Mygdonius (mod.
The site of Nisibis, on the great road between the Tigris and the Mediterranean, and commanding alike the mountain country to the north and the then fertile plain to the south, gave it an importance which began during the Assyrian period and continued under the Seleucid empire.
14 Nisibis was the residence of the kings of Armenia, and there Tigranes had his treasure-houses.