mosaicism

mosaicism Definition

mo·sai·cism (mō zā′i siz′əm)

noun

the condition existing when tissues of different genetic makeup occur in the same organism

Etymology: mosaic, + -ism

mosaicism Usage Examples

Adjective modifier

somatic: Such gross somatic mosaicism was not observed in three other lines examined, further emphasizing a role for flanking DNA in modulating repeat stability.
genetic: Furthermore, the only abnormal genes were found in abnormal lung and kidney tissue, arguing against genetic mosaicism.

Noun used with modifier

germline: Specifically, in 2 % of patients, the mutated TSC gene is not detected in either parent because of germline mosaicism.

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