Sentence Examples


  • Histiocytosis X or LCH is a family of related conditions, which are characterized by a distinct inflammatory and proliferative process but which differ from each other regarding what parts of the body are involved.
  • Histiocytosis X is a generic term that refers to an increase in the number of histiocytes, a type of white blood cell that acts as a scavenger to remove foreign material from the blood and tissues.
  • Research that demonstrated Langerhans cell involvement as well as histiocytes led to a proposal that the term Langerhans cell histiocytosis (LCH) be used in place of histiocytosis X.
  • The symptoms of histiocytosis are caused by substances called cytokines and prostaglandins, which are normally produced by histiocytes and act as messengers between cells.
  • Histiocytosis X is a rare disorder affecting only approximately one in 200,000 children or adults each year.