denature

(dē nāc̸hər)

transitive verb denatured, denaturing

  1. to change the nature of; take natural qualities away from
  2. to make (alcohol, etc.) unfit for human consumption without spoiling for other uses
  3. to change the structure of (a protein) by heat, acids, alkalies, etc., so that the original properties are greatly changed or eliminated
  4. to add a nonfissionable isotope to (a fissionable isotope) so that the mixture cannot be used in nuclear bombs but can still be used as fuel material

Origin: ML denaturare: see de- & nature

Related Forms:

See denature in American Heritage Dictionary 4

transitive verb de·na·tured, de·na·tur·ing, de·na·tures
  1. To change the nature or natural qualities of.
  2. To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).
  3. Biochemistry
    a. To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
    b. To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
  4. Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.

Related Forms:

  • de·naˈtur·ant noun
  • de·naˌtur·aˈtion noun

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