the primary lesion, sore, or ulcer of any of various diseases, esp. of syphilis
Origin of chancreFr: see cancer
- A dull red, hard, insensitive lesion that is the first manifestation of syphilis.
- An ulcer located at the initial point of entry of a pathogen.
Origin of chancreFrench, from Old French, from Latin cancer, tumor, crab; see kar- in Indo-European roots.