Disorders such as Apert's Syndrome can cause midface hypoplasia.
It is often associated with other craniofacial abnormalities, including Crouzon syndrome, Apert syndrome, Pfeiffer syndrome, and Saethre-Chotzen syndrome.
Other genetic syndromes, such as Crouzon syndrome, Apert syndrome, and Pfeiffer syndrome, are associated with craniosynostosis.
Apert syndrome-A craniofacial abnormality characterized by abnormal head shape, small upper jaw, and fusion of fingers and toes.
Children born with co-existing craniofacial conditions, such as Apert syndrome, which affects the growth of the jaw, may benefit from a technique called mandibular bone lengthening or distraction osteogenesis.