Salicylic acid and salicin (q.v.) share the properties common to the group of aromatic acids, which, as a group, are antiseptic without being toxic to man - a property practically unique; are unstable in the body; are antipyretic and analgesic; and diminish the excretion of urea by the kidneys.
The antipyretic action which considerable doses of aconite display is not specific, but is the result of its influence on the circulation and respiration and of its slight diaphoretic action.
It follows that the drug is an antipyretic, and it is hence largely used in fevers as a means of reducing the temperature.
According to Sir Thomas Fraser nothing else can compete with alcohol as a food in desperate febrile cases, and to this use must be added its antipyretic power already explained and its action as a soporific. During its administration in febrile cases the drug must be most carefully watched, as its action may prove deleterious to the nervous system and the circulation in certain classes of patient.
In medicine antipyrine ("phenazonum") has been used as an analgesic and antipyretic. The dose is 5-20 grs., but on account of its depressant action on the heart, and the toxic effects to which it occasionally gives rise, it is now but little used.
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